Antigenic Variation Among Adenovirus Type 12 Strains

Antigenic Variation Among Adenovirus Type 12 Strains.

Recent reports relative to the oncogenicity of adenovirus types 12 and 18 (Trentin, Yabe, and Taylor, Science 137:835, 1962; Huebner, Rowe, and Lane, Proc. Natl. Acad. Sci. U.S. 48:2051, 1962) have caused a renewed surge of interest in the adenovirus group. In addition to the prototype strain Huie, Huebner and co-workers investigated eight adenovirus type 12 strains, recovered from anal swabs o...

Antigenic variation between rabies virus strains and its relevance in vaccine production and potency testing

Use of absorbed antisera for demonstration of antigenic variation among strains of Legionella pneumophila serogroup 1.

Antigenic typing of strains of Legionella pneumophila serogroup 1 (Lp1) has been shown to be useful in epidemiological studies of outbreaks of legionellosis. Selective absorption of rabbit antibodies produced against five strains of Lp1 resulted in the recognition of 17 somatic types among the 176 strains tested. A comparison was made of our results and those obtained by McKinney et al. (Zentra...

Adenovirus type 12-rat embryo transformation system.

Adenovirus type 12 (Huie) inoculated into cultures of primary whole rat embryo produced foci of morphologically altered cells. The number and identification of these transformed areas was dependent upon the calcium concentration of the medium; more foci appeared in 0.1 mm than in 1.8 mm calcium. Cell lines derived from these inoculated cultures did not yield infectious virus, and also were simi...

Antigenic differences among porcine circovirus type 2 strains, as demonstrated by the use of monoclonal antibodies.

This study examined whether antigenic differences among porcine circovirus type 2 (PCV-2) strains could be detected using monoclonal antibodies (mAbs). A subtractive immunization protocol was used for the genotype 2 post-weaning multisystemic wasting syndrome (PMWS)-associated PCV-2 strain Stoon-1,010. Sixteen stable hybridomas that produced mAbs with an immunoperoxidase monolayer assay (IPMA) ...